Chain hitting the front derailleur

You should never use that gear combination (hardest in the back, easiest in the front) it’s called “cross chaining” and it’s inefficient, leads to a not tight chain, as you can see from how high your rear derailleur is up, and also causes more rapid wear on your drivetrain. By the time you want it to be that hard to pedal you should be using the big ring.

It is very common to have weird rubbing in this position because of the loose chain and also how far over the chain is. You could adjust the lower limit on your front derailleur to push the cage further over and away from the chain, but it would likely make the chain rub on the other side where you actually should be using it in the easy gears.

Anyways, if you actually want to learn some mechanics, how the FD works, and how it should be set-up, please watch this video while working on your bike:

https://www.parktool.com/en-us/blog/repair-help/front-derailleur-adjustment

If you have no idea how the FD works in general, watch the other video he recommends at the beginning.

I generally avoid small-small, but shift 1 “click” on the front derailleur to stop the rub in the rare occasion when small-small makes sense.

Front derailleurs can be finicky
If it’s not hitting when you aren’t cross chained, you’re good. If it is, tighten cable adjuster till it goes away. Make your high limit screw isn’t stopping it.

It always surprises me that people spend upwards of $/£1000 and don’t know about cross-chaining, and the trim feature to eliminate chain rub. Don’t use low front/high rear, nor, high front/low rear. The chain is at an angle, wears faster, will definitely rub. This is not a defect of the bike, it’s common user error.