Many cancer cell lines preferentially consume glutamine. Does this mean that glutamine itself fuels cancer? In this video, we examine the evidence.
As always, this is presented as information, not as medical advice. Medical advice should come from an appropriately accredited medical professional familiar with your unique circumstances.
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Cancer Self-Defense 101: Quick Tips to Help You Survive
In this video we examine the role of glutamine in cancer progression as always these ideas are discussed in more depth in the book cancer self-defense 101 quick tips to help you survive all citations for studies quoted in this video can be found in the book’s bibliography at cancer selfdefense 101.com
Glutamine is a non-essential amino acid it is non-essential because the body can synthesize it we do not need to consume it from the diet amino acids we need to consume from the diet are called essential amino acids cancer cells consume glutamine in inordinate amounts the heiler cervical
Cancer cell line has been found to consume 100 times more glutamine than any other amino acid the nitrogen and glutamine is used by cancer to build nucleic acids essential for cell reproduction glutamine also participates in the uptake of non-essential amino acids from the extracellular environment for use by
Cancer cells it is also used by cancer cells in the synthesis of glutathion Cancer’s main defense against the reactive oxygen species that should be killing it many cancers show a particular dependence upon glutamine including Advanced Cancers and brain cancers other cancers that show an extreme dependence of on glutamine are
Pancreatic cancer acute myogenous leukemia small cell lung cancer breast cancer especially triple negative and melanoma there is no cancer cell line that we’re aware of where glutamine inhibition didn’t at least arrest cancer cell proliferation mice models of medul blastoma a brain cancer fed a glutamine restricted diet had about a 50% longer
Survival time than mice not fed a glutamine restricted diet additionally mice fed the glutamine restricted diet were found to have lower blood levels of glutamine despite the fact that mice can synthesize their own glutamine just as humans can a glutamine restricted diet lowers blood glutamine levels please keep in mind that it is
Impossible to completely eliminate glucose and glutamine from the human diet or even from the body as the body can synthesize both glucose and glutamine the idea is to minimize them for more information on the role of glutamine in cancer progression see the book cancer selfdefense 101 quick tips to help you survive